Epigenetic regulation in neural crest development

The neural crest is a migratory and multipotent cell population that plays a crucial role in many aspects of embryonic development. In all vertebrate embryos, these cells emerge from the dorsal neural tube then migrate long distances to different regions of the body, where they contribute to formati...

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Detalhes bibliográficos
Autores: Hu, Na, Strobl Mazulla, Pablo Hernan, Bronner, Marieanne E.
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2014
País:Argentina
Recursos:Consejo Nacional de Investigaciones Científicas y Técnicas
Repositorio:CONICET Digital (CONICET)
Idioma:inglés
OAI Identifier:oai:ri.conicet.gov.ar:11336/33272
Acesso em linha:http://hdl.handle.net/11336/33272
Access Level:acceso abierto
Palavra-chave:Epigenetic
Neural Crest
Development
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
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spelling Epigenetic regulation in neural crest development Hu, Na Strobl Mazulla, Pablo Hernan Bronner, Marieanne E. Epigenetic Neural Crest Development https://purl.org/becyt/ford/1.6 https://purl.org/becyt/ford/1 The neural crest is a migratory and multipotent cell population that plays a crucial role in many aspects of embryonic development. In all vertebrate embryos, these cells emerge from the dorsal neural tube then migrate long distances to different regions of the body, where they contribute to formation of many cell types and structures. These include much of the peripheral nervous system, craniofacial skeleton, smooth muscle, and pigmentation of the skin. The best-studied regulatory events guiding neural crest development are mediated by transcription factors and signaling molecules. In recent years, however, growing evidence supports an important role for epigenetic regulation as an additional mechanism for controlling the timing and level of gene expression at different stages of neural crest development. Here, we summarize the process of neural crest formation, with focus on the role of epigenetic regulation in neural crest specification, migration, and differentiation as well as in neural crest related birth defects and diseases. Fil: Hu, Na. California Institute of Technology. Pasadena; Estados Unidos Fil: Strobl Mazulla, Pablo Hernan. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Biotecnológicas. Instituto de Investigaciones Biotecnológicas "Dr. Raúl Alfonsín" (sede Chascomús). Universidad Nacional de San Martín. Instituto de Investigaciones Biotecnológicas. Instituto de Investigaciones Biotecnológicas "Dr. Raúl Alfonsín" (sede Chascomús); Argentina Fil: Bronner, Marieanne E.. California Institute of Technology. Pasadena; Estados Unidos Academic Press Inc Elsevier Science http://hdl.handle.net/11336/33272 Hu, Na; Strobl Mazulla, Pablo Hernan; Bronner, Marieanne E.; Epigenetic regulation in neural crest development; Academic Press Inc Elsevier Science; Developmental Biology; 396; 2; 11-2014; 159-168 0012-1606 CONICET Digital CONICET
title Epigenetic regulation in neural crest development
spellingShingle Epigenetic regulation in neural crest development
Hu, Na
Epigenetic
Neural Crest
Development
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
title_short Epigenetic regulation in neural crest development
title_full Epigenetic regulation in neural crest development
title_fullStr Epigenetic regulation in neural crest development
title_full_unstemmed Epigenetic regulation in neural crest development
title_sort Epigenetic regulation in neural crest development
author Hu, Na
author_facet Hu, Na
Strobl Mazulla, Pablo Hernan
Bronner, Marieanne E.
author_role author
author2 Strobl Mazulla, Pablo Hernan
Bronner, Marieanne E.
author2_role author
author
topic Epigenetic
Neural Crest
Development
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
topic_facet Epigenetic
Neural Crest
Development
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
description The neural crest is a migratory and multipotent cell population that plays a crucial role in many aspects of embryonic development. In all vertebrate embryos, these cells emerge from the dorsal neural tube then migrate long distances to different regions of the body, where they contribute to formation of many cell types and structures. These include much of the peripheral nervous system, craniofacial skeleton, smooth muscle, and pigmentation of the skin. The best-studied regulatory events guiding neural crest development are mediated by transcription factors and signaling molecules. In recent years, however, growing evidence supports an important role for epigenetic regulation as an additional mechanism for controlling the timing and level of gene expression at different stages of neural crest development. Here, we summarize the process of neural crest formation, with focus on the role of epigenetic regulation in neural crest specification, migration, and differentiation as well as in neural crest related birth defects and diseases.
publishDate 2014
format article
status_str publishedVersion
url http://hdl.handle.net/11336/33272
identifier_str_mv Hu, Na; Strobl Mazulla, Pablo Hernan; Bronner, Marieanne E.; Epigenetic regulation in neural crest development; Academic Press Inc Elsevier Science; Developmental Biology; 396; 2; 11-2014; 159-168
0012-1606
CONICET Digital
CONICET
language eng
eu_rights_str_mv openAccess
publisher Academic Press Inc Elsevier Science
institution Consejo Nacional de Investigaciones Científicas y Técnicas
collection CONICET Digital (CONICET)
reponame_str CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
_version_ 1878403967068667904
publishDateSort 2014
author_browse Bronner, Marieanne E.
Hu, Na
Strobl Mazulla, Pablo Hernan
publisherStr Academic Press Inc Elsevier Science
score 6,8972664

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