Jet lag, circadian rhythm sleep disturbances and depression : the role of melatonin and its analogs

Fil: Srinivasan, Venkataramanujan. Sri Sathya Sai Medical Educational and Research Foundation; India

Detalles Bibliográficos
Autores: Srinivasan, Venkataramanujan, Singh, Jarnail, Pandi Perumal, Seithikurippu R., Spence, David Warren, Brown, Gregory M., Cardinali, Daniel Pedro
Tipo de recurso: artículo
Estado:Versión enviada para evaluación y publicación
Fecha de publicación:2010
País:Argentina
Institución:Pontificia Universidad Católica Argentina
Repositorio:Repositorio Institucional (UCA)
Idioma:inglés
OAI Identifier:oai:ucacris:123456789/1621
Acceso en línea:https://repositorio.uca.edu.ar/handle/123456789/1621
Access Level:acceso abierto
Palabra clave:RITMO CIRCADIANO
DEPRESION
MELATONINA
INSOMNIO
FATIGA
TRASTORNOS DEL SUEÑO
RAMELTEON
TASIMELTEON
TRASTONOS CRONOBIOLOGICOS
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network_name_str Argentina
spelling Jet lag, circadian rhythm sleep disturbances and depression : the role of melatonin and its analogs Srinivasan, Venkataramanujan Singh, Jarnail Pandi Perumal, Seithikurippu R. Spence, David Warren Brown, Gregory M. Cardinali, Daniel Pedro RITMO CIRCADIANO DEPRESION MELATONINA INSOMNIO FATIGA TRASTORNOS DEL SUEÑO RAMELTEON TASIMELTEON TRASTONOS CRONOBIOLOGICOS Fil: Srinivasan, Venkataramanujan. Sri Sathya Sai Medical Educational and Research Foundation; India Fil: Srinivasan, Venkataramanujan. Karpagam University. Facultad de Medicina. Departamento de Fisiología; India Fil: Singh, Jarnail. Civil Aviation Authority; Singapur Fil: Pandi Perumal, Seithikurippu R. Somnogen Inc; Estados Unidos Fil: Spence, David Warren. Sleep and Alertness Clinic; Estados Unidos Fil: Brown, Gregory M. Centre for Addiction and Mental Health; Canadá Fil: Cardinali, Daniel Pedro. Pontificia Universidad Católica Argentina. Facultad de Medicina. Departamento de Docencia e Investigación; Argentina Abstract: Travelling through several time zones results in a constellation of symptoms known as jet lag. These include reduced alertness, daytime fatigue, loss of appetite, reduced cognitive skills, and disruptions to sleep/wakefulness and other circadian rhythms. In susceptible air travel passengers, jet lag may exacerbate affective illness ans result in psychiatric morbidity. It is suggested that dysregulation of circadian rhythms and melatonin secretion represents the common underlying factor in jet lag and other circadian disorders. Hence the effective management of jet lag requires timely application of the well known chronobiotic melatonin. Recent studies have emphasized the importance of strategically timed administrations of melatonin and appropriate limited exposure to environmental schedules. However, with the introduction of the melatonergic agonists such as ramelteon and tasimelteon, which have both a strong affinity for MT1 and MT2 melatonin receptors and a longer half life, a new therapeutic option now exists for treating the sleep disturbances associated with jet lag. The melatonin analogs are unique inasmuch as they can also enhance daytime alertness. Since jet lag exacerbates affective disorders in susceptible air‐travel passengers, and can thus produce psychiatric morbidity, there is a need for an effective antidepressant with chronobiotic properties. In this regard the recently introduced melatonergic antidepressant agomelatine, which has successfully established its supremacy over other antidepressants in having chronobiotic effects, represents a good choice for treating depressive symptoms that are associated with jet lag. Springer https://repositorio.uca.edu.ar/handle/123456789/1621 0741-238X (impreso) 1865-8652 (online) 10.1007/s12325-010-0065-y Srinivasan, V., et al. Jet lag, circadian rhythm sleep disturbances and depression : the role of melatonin and its analogs [en línea]. Preprint de artículo publicado en Advances in Therapy. 2010, 27 (11). doi:10.1007/s12325-010-0065-y. Disponible en: https://repositorio.uca.edu.ar/handle/123456789/1621
title Jet lag, circadian rhythm sleep disturbances and depression : the role of melatonin and its analogs
spellingShingle Jet lag, circadian rhythm sleep disturbances and depression : the role of melatonin and its analogs
Srinivasan, Venkataramanujan
RITMO CIRCADIANO
DEPRESION
MELATONINA
INSOMNIO
FATIGA
TRASTORNOS DEL SUEÑO
RAMELTEON
TASIMELTEON
TRASTONOS CRONOBIOLOGICOS
title_short Jet lag, circadian rhythm sleep disturbances and depression : the role of melatonin and its analogs
title_full Jet lag, circadian rhythm sleep disturbances and depression : the role of melatonin and its analogs
title_fullStr Jet lag, circadian rhythm sleep disturbances and depression : the role of melatonin and its analogs
title_full_unstemmed Jet lag, circadian rhythm sleep disturbances and depression : the role of melatonin and its analogs
title_sort Jet lag, circadian rhythm sleep disturbances and depression : the role of melatonin and its analogs
author Srinivasan, Venkataramanujan
author_facet Srinivasan, Venkataramanujan
Singh, Jarnail
Pandi Perumal, Seithikurippu R.
Spence, David Warren
Brown, Gregory M.
Cardinali, Daniel Pedro
author_role author
author2 Singh, Jarnail
Pandi Perumal, Seithikurippu R.
Spence, David Warren
Brown, Gregory M.
Cardinali, Daniel Pedro
author2_role author
author
author
author
author
topic RITMO CIRCADIANO
DEPRESION
MELATONINA
INSOMNIO
FATIGA
TRASTORNOS DEL SUEÑO
RAMELTEON
TASIMELTEON
TRASTONOS CRONOBIOLOGICOS
topic_facet RITMO CIRCADIANO
DEPRESION
MELATONINA
INSOMNIO
FATIGA
TRASTORNOS DEL SUEÑO
RAMELTEON
TASIMELTEON
TRASTONOS CRONOBIOLOGICOS
description Fil: Srinivasan, Venkataramanujan. Sri Sathya Sai Medical Educational and Research Foundation; India
publishDate 2010
format article
status_str submittedVersion
url https://repositorio.uca.edu.ar/handle/123456789/1621
identifier_str_mv 0741-238X (impreso)
1865-8652 (online)
10.1007/s12325-010-0065-y
Srinivasan, V., et al. Jet lag, circadian rhythm sleep disturbances and depression : the role of melatonin and its analogs [en línea]. Preprint de artículo publicado en Advances in Therapy. 2010, 27 (11). doi:10.1007/s12325-010-0065-y. Disponible en: https://repositorio.uca.edu.ar/handle/123456789/1621
language eng
eu_rights_str_mv openAccess
publisher Springer
institution Pontificia Universidad Católica Argentina
collection Repositorio Institucional (UCA)
reponame_str Repositorio Institucional (UCA)
instname_str Pontificia Universidad Católica Argentina
_version_ 1878403982465957889
publishDateSort 2010
author_browse Brown, Gregory M.
Cardinali, Daniel Pedro
Pandi Perumal, Seithikurippu R.
Singh, Jarnail
Spence, David Warren
Srinivasan, Venkataramanujan
publisherStr Springer
score 6.9303427

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