Antibody dynamics during gestation in cows naturally infected with Neospora caninum from four dairy herds in Brazil

Neospora caninum has been described as an important cause of abortion in bovine worldwide. The objective of the present study was to characterize patterns of antibody dynamics during gestation in dairy cows naturally infected with N. caninum. Twelve N. caninum naturally infected cows were selected f...

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Detalles Bibliográficos
Autores: Cardoso, José Márcio Sbruzzi, Nishi, Sandra Mayumi, Funada, Mikaela Renata, Amaku, Marcos, Guimarãres Júnior, José da Silva, Gennari, Solange Maria
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2009
País:Brasil
Institución:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)
Repositorio:Brazilian Journal of Veterinary Research and Animal Science
Idioma:portugués
OAI Identifier:oai:revistas.usp.br:article/26789
Acceso en línea:https://www.revistas.usp.br/bjvras/article/view/26789
Access Level:acceso abierto
Palabra clave:Neospora caninum
Antibody dynamics
Antibody titer
Pregnancy
Bovine
Dinâmica de anticorpos
Título anticorpos
Gestação
Bovinos
Descripción
Sumario:Neospora caninum has been described as an important cause of abortion in bovine worldwide. The objective of the present study was to characterize patterns of antibody dynamics during gestation in dairy cows naturally infected with N. caninum. Twelve N. caninum naturally infected cows were selected from four dairy herds from Brazil and blood samples were monthly collected during pregnancy. Serum were tested for antibodies against N. caninum by Indirect Fluorescent Antibody Test (IFAT). During this period, all cows remained clinically normal and gave birth to healthy calves. The cows remained seropositives during the study and N. caninum IFAT titers ranged from 100 to 12,800; only animal 234 presented one negative result in the first month of pregnancy. Significant differences of N. caninum IFAT titers were found between months from 1 to 9 of pregnancy by the Friedman Test (P<0.001). The statistical analysis showed an increase of N. caninum antibody titers from second and third trimester of pregnancy in relation to first trimester. High titers were observed in few cows after month fifth of pregnancy. This study showed a variation of specific antibody levels in seropositive cows during different gestational periods. The highest values were observed during the second and third trimester. The antibody increase after the fifth month of gestation was not associated to abortion.