Literature Review of the Use of Scintimammography with Technetium-99m Methoxyisobutylisonitrile (99mTc-MIBI) for the Differential Diagnosis of Breast Carcinoma

Mammography has proven to be quite sensitive in detecting breast lesions, but frequently it cannot be used to accurately differentiate benign from malignant lesions. Many breast cancer experts believe that a better diagnostic imaging tool is needed, given that an estimated 700,000 breast biopsies ar...

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Bibliographic Details
Authors: Costa, Marly G.F., Costa Filho, Cícero F.F., Moura Jr, Lincoln de Assis
Format: article
Status:Published version
Publication Date:2001
Country:Brasil
Institution:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
Repository:Revista Brasileira de Cancerologia (Online)
Language:Portuguese
OAI Identifier:oai:rbc.inca.gov.br:article/2395
Online Access:https://rbc.inca.gov.br/index.php/revista/article/view/2395
Access Level:Open access
Keyword:Cintilografia mamária
Neoplasias mamárias
Diagnóstico por imagem
MIBI-99mTc
Scintimammography
Breast neoplasms
Imaging diagnosis
Tc-99m MIBI
Description
Summary:Mammography has proven to be quite sensitive in detecting breast lesions, but frequently it cannot be used to accurately differentiate benign from malignant lesions. Many breast cancer experts believe that a better diagnostic imaging tool is needed, given that an estimated 700,000 breast biopsies are done every year, with only 1 out of 4 finding cancer. Many other imaging techniques have been studied. The scintimammography using Technetium-99m MIBI is a technique that has been studied over the last few years. The results obtained with these studies suggest that the scintimammography is a promising tool for diagnosing cancer. In this article we describe the technical aspects of scintimammography as proposed by Khalkhali (11) and present the results of several studies published about this new non-invasive test.