Editorial: Nucleic acid-based aptamers in therapeutics and diagnostics

Aptamers have emerged as versatile and powerful tools in the fields of therapeutics and diagnostics. These molecules are single-stranded nucleic acids—either DNA or RNA—that fold into unique three-dimensional structures, allowing them to selectively bind to target molecules with high affinity and sp...

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Detalles Bibliográficos
Autores: Aviñó, Anna, Fàbrega, Carme, Gargallo, Raimundo, Mazzini, Stefania, Riccardi, Claudia
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/343968
Acceso en línea:http://hdl.handle.net/10261/343968
https://api.elsevier.com/content/abstract/scopus_id/85182468500
Access Level:acceso abierto
Palabra clave:Therapeutics
SELEX
Aptamers
Diagnostics
Nucleic acids (DNA and RNA)
http://metadata.un.org/sdg/3
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Descripción
Sumario:Aptamers have emerged as versatile and powerful tools in the fields of therapeutics and diagnostics. These molecules are single-stranded nucleic acids—either DNA or RNA—that fold into unique three-dimensional structures, allowing them to selectively bind to target molecules with high affinity and specificity. They can be identified through an iterative selection process called SELEX (Systematic Evolution of Ligands by EXponential enrichment).