An intensive, structured, mobile devices-based healthcare intervention to optimize the lipid-lowering therapy improves lipid control after an acute coronary syndrome

Aims: despite the evidence, lipid-lowering treatment (LLT) in secondary prevention remains insufficient, and a low percentage of patients achieve the recommended LDL cholesterol (LDLc) levels by the guidelines. We aimed to evaluate the efficacy of an intensive, mobile devices-based healthcare lipid-...

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Autores: Ruiz-Bustillo, Sonia, Badosa Marcé, Neus, Cabrera-Aguilera, Ignacio, Ivern Díaz, Consol, Llagostera Martín, Marc, Mojón Álvarez, Diana, Vicente Elcano, Miren, Ribas Barquet, Núria, Recasens, Lluís, Marti-Almor, Julio, Cladellas Capdevila, M.Mercedes, Farré López, Núria
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:España
Institución:Universitat Pompeu Fabra
Repositorio:Repositorio Digital de la UPF
OAI Identifier:oai:repositori.upf.edu:10230/55677
Acceso en línea:http://hdl.handle.net/10230/55677
http://dx.doi.org/10.3389/fcvm.2022.916031
Access Level:acceso abierto
Palabra clave:Cardiovascular risk factors
Ischemic heart disease
Lipid-lowering therapy
Mobile devices-based healthcare
Secondary prevention
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spelling An intensive, structured, mobile devices-based healthcare intervention to optimize the lipid-lowering therapy improves lipid control after an acute coronary syndromeRuiz-Bustillo, SoniaBadosa Marcé, NeusCabrera-Aguilera, IgnacioIvern Díaz, ConsolLlagostera Martín, MarcMojón Álvarez, DianaVicente Elcano, MirenRibas Barquet, NúriaRecasens, LluísMarti-Almor, JulioCladellas Capdevila, M.MercedesFarré López, NúriaCardiovascular risk factorsIschemic heart diseaseLipid-lowering therapyMobile devices-based healthcareSecondary preventionAims: despite the evidence, lipid-lowering treatment (LLT) in secondary prevention remains insufficient, and a low percentage of patients achieve the recommended LDL cholesterol (LDLc) levels by the guidelines. We aimed to evaluate the efficacy of an intensive, mobile devices-based healthcare lipid-lowering intervention after hospital discharge in patients hospitalized for acute coronary syndrome (ACS). Methods and results: ambiespective register in which a mobile devices-based healthcare intervention including periodic follow-up, serial lipid level controls, and optimization of lipid-lowering therapy, if appropriate, was assessed in terms of serum lipid-level control at 12 weeks after discharge. A total of 497 patients, of which 462 (93%) correctly adhered to the optimization protocol, were included in the analysis. At the end of the optimization period, 327 (70.7%) patients had LDLc levels ≤ 70 mg/dL. 40% of patients in the LDLc ≤ 70 mg/dL group were upgraded to very-high intensity lipid-lowering ability therapy vs. 60.7% in the LDLc > 70 mg/dL group, p < 0.001. Overall, 38.5% of patients had at least a change in their LLT. Side effects were relatively infrequent (10.7%). At 1-year follow-up, LDLc levels were measured by the primary care physician in 342 (68.8%) of the whole cohort of 497 patients. In this group, 71.1% of patients had LDLc levels ≤ 70 mg/dL. Conclusion: an intensive, structured, mobile devices-based healthcare intervention after an ACS is associated with more than 70% of patients reaching the LDLc levels recommended by the clinical guidelines. In patients with LDLc measured at 1-year follow-up, 71.1% had LDLc levels ≤ 70 mg/dL.Frontiers202320232022info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10230/55677http://dx.doi.org/10.3389/fcvm.2022.916031reponame:Repositorio Digital de la UPFinstname:Universitat Pompeu FabraInglésCopyright © 2022 Ruiz-Bustillo, Badosa, Cabrera-Aguilera, Ivern, Llagostera, Mojón, Vicente, Ribas, Recasens, Martí-Almor, Cladellas and Farré. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) http://creativecommons.org/licenses/by/4.0/. The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.http://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:repositori.upf.edu:10230/556772026-06-12T07:21:37Z
dc.title.none.fl_str_mv An intensive, structured, mobile devices-based healthcare intervention to optimize the lipid-lowering therapy improves lipid control after an acute coronary syndrome
title An intensive, structured, mobile devices-based healthcare intervention to optimize the lipid-lowering therapy improves lipid control after an acute coronary syndrome
spellingShingle An intensive, structured, mobile devices-based healthcare intervention to optimize the lipid-lowering therapy improves lipid control after an acute coronary syndrome
Ruiz-Bustillo, Sonia
Cardiovascular risk factors
Ischemic heart disease
Lipid-lowering therapy
Mobile devices-based healthcare
Secondary prevention
title_short An intensive, structured, mobile devices-based healthcare intervention to optimize the lipid-lowering therapy improves lipid control after an acute coronary syndrome
title_full An intensive, structured, mobile devices-based healthcare intervention to optimize the lipid-lowering therapy improves lipid control after an acute coronary syndrome
title_fullStr An intensive, structured, mobile devices-based healthcare intervention to optimize the lipid-lowering therapy improves lipid control after an acute coronary syndrome
title_full_unstemmed An intensive, structured, mobile devices-based healthcare intervention to optimize the lipid-lowering therapy improves lipid control after an acute coronary syndrome
title_sort An intensive, structured, mobile devices-based healthcare intervention to optimize the lipid-lowering therapy improves lipid control after an acute coronary syndrome
dc.creator.none.fl_str_mv Ruiz-Bustillo, Sonia
Badosa Marcé, Neus
Cabrera-Aguilera, Ignacio
Ivern Díaz, Consol
Llagostera Martín, Marc
Mojón Álvarez, Diana
Vicente Elcano, Miren
Ribas Barquet, Núria
Recasens, Lluís
Marti-Almor, Julio
Cladellas Capdevila, M.Mercedes
Farré López, Núria
author Ruiz-Bustillo, Sonia
author_facet Ruiz-Bustillo, Sonia
Badosa Marcé, Neus
Cabrera-Aguilera, Ignacio
Ivern Díaz, Consol
Llagostera Martín, Marc
Mojón Álvarez, Diana
Vicente Elcano, Miren
Ribas Barquet, Núria
Recasens, Lluís
Marti-Almor, Julio
Cladellas Capdevila, M.Mercedes
Farré López, Núria
author_role author
author2 Badosa Marcé, Neus
Cabrera-Aguilera, Ignacio
Ivern Díaz, Consol
Llagostera Martín, Marc
Mojón Álvarez, Diana
Vicente Elcano, Miren
Ribas Barquet, Núria
Recasens, Lluís
Marti-Almor, Julio
Cladellas Capdevila, M.Mercedes
Farré López, Núria
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Cardiovascular risk factors
Ischemic heart disease
Lipid-lowering therapy
Mobile devices-based healthcare
Secondary prevention
topic Cardiovascular risk factors
Ischemic heart disease
Lipid-lowering therapy
Mobile devices-based healthcare
Secondary prevention
description Aims: despite the evidence, lipid-lowering treatment (LLT) in secondary prevention remains insufficient, and a low percentage of patients achieve the recommended LDL cholesterol (LDLc) levels by the guidelines. We aimed to evaluate the efficacy of an intensive, mobile devices-based healthcare lipid-lowering intervention after hospital discharge in patients hospitalized for acute coronary syndrome (ACS). Methods and results: ambiespective register in which a mobile devices-based healthcare intervention including periodic follow-up, serial lipid level controls, and optimization of lipid-lowering therapy, if appropriate, was assessed in terms of serum lipid-level control at 12 weeks after discharge. A total of 497 patients, of which 462 (93%) correctly adhered to the optimization protocol, were included in the analysis. At the end of the optimization period, 327 (70.7%) patients had LDLc levels ≤ 70 mg/dL. 40% of patients in the LDLc ≤ 70 mg/dL group were upgraded to very-high intensity lipid-lowering ability therapy vs. 60.7% in the LDLc > 70 mg/dL group, p < 0.001. Overall, 38.5% of patients had at least a change in their LLT. Side effects were relatively infrequent (10.7%). At 1-year follow-up, LDLc levels were measured by the primary care physician in 342 (68.8%) of the whole cohort of 497 patients. In this group, 71.1% of patients had LDLc levels ≤ 70 mg/dL. Conclusion: an intensive, structured, mobile devices-based healthcare intervention after an ACS is associated with more than 70% of patients reaching the LDLc levels recommended by the clinical guidelines. In patients with LDLc measured at 1-year follow-up, 71.1% had LDLc levels ≤ 70 mg/dL.
publishDate 2022
dc.date.none.fl_str_mv 2022
2023
2023
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10230/55677
http://dx.doi.org/10.3389/fcvm.2022.916031
url http://hdl.handle.net/10230/55677
http://dx.doi.org/10.3389/fcvm.2022.916031
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Frontiers
publisher.none.fl_str_mv Frontiers
dc.source.none.fl_str_mv reponame:Repositorio Digital de la UPF
instname:Universitat Pompeu Fabra
instname_str Universitat Pompeu Fabra
reponame_str Repositorio Digital de la UPF
collection Repositorio Digital de la UPF
repository.name.fl_str_mv
repository.mail.fl_str_mv
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