Metacognitive training (MCT) for psychosis: a systematic review and grade recommendations

Background: Recent meta-analyses support the inclusion of cognitive behavioral therapy (CBT) in schizophrenia treatment. Metacognitive Training (MCT) for psychosis is a psychoeducational program derived from CBT, with most meta-analyses showing favorable results. Although meta-analyses are commonly...

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Autores: Goncalves, Adrien|||0009-0000-4834-3043, Ochoa Güerre, Susana|||0000-0001-6792-1080, Moritz, Steffen, Gaweda, Lukasz, Cavieres, Álvaro, König, Caroline|||0000-0002-7543-8686, Fischer, Rabea, Meinhart, Antonia, Lamarca, María, Ayesa Arriola, Rosa|||0000-0003-0570-5352, Balzan, Ryan|||0000-0003-2007-4317, Böge, Kerem|||0000-0001-8263-4936, Lecomte, Tania|||0000-0002-0340-3759, Raffard, Stéphane|||0000-0001-5563-0323, Berna, Fabrice
Tipo de recurso: artículo
Fecha de publicación:2025
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/438939
Acceso en línea:https://hdl.handle.net/2117/438939
https://dx.doi.org/10.1192/j.eurpsy.2025.10027
Access Level:acceso abierto
Palabra clave:MCT
Metacognitive training
Systematic review
Grade recommendation
Psychosis
Schizophrenia
Àrees temàtiques de la UPC::Ciències de la salut::Salut mental
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oai_identifier_str oai:upcommons.upc.edu:2117/438939
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spelling Metacognitive training (MCT) for psychosis: a systematic review and grade recommendations Goncalves, Adrien|||0009-0000-4834-3043 Ochoa Güerre, Susana|||0000-0001-6792-1080 Moritz, Steffen Gaweda, Lukasz Cavieres, Álvaro König, Caroline|||0000-0002-7543-8686 Fischer, Rabea Meinhart, Antonia Lamarca, María Ayesa Arriola, Rosa|||0000-0003-0570-5352 Balzan, Ryan|||0000-0003-2007-4317 Böge, Kerem|||0000-0001-8263-4936 Lecomte, Tania|||0000-0002-0340-3759 Raffard, Stéphane|||0000-0001-5563-0323 Berna, Fabrice MCT Metacognitive training Systematic review Grade recommendation Psychosis Schizophrenia Àrees temàtiques de la UPC::Ciències de la salut::Salut mental Background: Recent meta-analyses support the inclusion of cognitive behavioral therapy (CBT) in schizophrenia treatment. Metacognitive Training (MCT) for psychosis is a psychoeducational program derived from CBT, with most meta-analyses showing favorable results. Although meta-analyses are commonly used in clinical practice to guide evidence-based decision-making, the grading system provides complementary results by offering a structured approach for assessing the strength and reliability of evidence and deriving grades of recommendations accordingly. Methods: Our research applies the guidelines from the World Federation of Societies of Biological Psychiatry (WFSBP) to propose grades of recommendation for MCT for psychosis, analyzing 38 randomized controlled trials (RCTs) (n = 1942) and 10 meta63 analyses. The primary outcome was positive symptoms, with secondary measures including negative symptoms, general psychopathology, self-esteem, functioning, insight, and cognitive function. Results: Our findings are primarily based on the risks of bias attributed to RCTs (11 high, 19 moderate, 6 low) and, when necessary, on the overall confidence attributed to meta68 analyses (3 low, 7 critically low). According to the WFSBP guidelines, strong recommendations should be made for using MCT for psychosis to improve post-treatment positive symptoms, delusions, and total psychotic symptoms (WFSBP-grade 1). Limited recommendation (WFSBP-grade 2) could be made for using MCT to improve post72 treatment visuospatial abilities and to maintain benefits over time in psychopathology, functioning, self-esteem, episodic memory, and attention. Conclusions: MCT for psychosis is an evidence-based program, especially for positive symptoms, with long-lasting clinical benefits. These recommendations should be interpreted with caution given potential residual biases and heterogeneity among studies. Peer Reviewed https://hdl.handle.net/2117/438939 https://dx.doi.org/10.1192/j.eurpsy.2025.10027
title Metacognitive training (MCT) for psychosis: a systematic review and grade recommendations
spellingShingle Metacognitive training (MCT) for psychosis: a systematic review and grade recommendations
Goncalves, Adrien|||0009-0000-4834-3043
MCT
Metacognitive training
Systematic review
Grade recommendation
Psychosis
Schizophrenia
Àrees temàtiques de la UPC::Ciències de la salut::Salut mental
title_short Metacognitive training (MCT) for psychosis: a systematic review and grade recommendations
title_full Metacognitive training (MCT) for psychosis: a systematic review and grade recommendations
title_fullStr Metacognitive training (MCT) for psychosis: a systematic review and grade recommendations
title_full_unstemmed Metacognitive training (MCT) for psychosis: a systematic review and grade recommendations
title_sort Metacognitive training (MCT) for psychosis: a systematic review and grade recommendations
author Goncalves, Adrien|||0009-0000-4834-3043
author_facet Goncalves, Adrien|||0009-0000-4834-3043
Ochoa Güerre, Susana|||0000-0001-6792-1080
Moritz, Steffen
Gaweda, Lukasz
Cavieres, Álvaro
König, Caroline|||0000-0002-7543-8686
Fischer, Rabea
Meinhart, Antonia
Lamarca, María
Ayesa Arriola, Rosa|||0000-0003-0570-5352
Balzan, Ryan|||0000-0003-2007-4317
Böge, Kerem|||0000-0001-8263-4936
Lecomte, Tania|||0000-0002-0340-3759
Raffard, Stéphane|||0000-0001-5563-0323
Berna, Fabrice
author_role author
author2 Ochoa Güerre, Susana|||0000-0001-6792-1080
Moritz, Steffen
Gaweda, Lukasz
Cavieres, Álvaro
König, Caroline|||0000-0002-7543-8686
Fischer, Rabea
Meinhart, Antonia
Lamarca, María
Ayesa Arriola, Rosa|||0000-0003-0570-5352
Balzan, Ryan|||0000-0003-2007-4317
Böge, Kerem|||0000-0001-8263-4936
Lecomte, Tania|||0000-0002-0340-3759
Raffard, Stéphane|||0000-0001-5563-0323
Berna, Fabrice
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
topic MCT
Metacognitive training
Systematic review
Grade recommendation
Psychosis
Schizophrenia
Àrees temàtiques de la UPC::Ciències de la salut::Salut mental
topic_facet MCT
Metacognitive training
Systematic review
Grade recommendation
Psychosis
Schizophrenia
Àrees temàtiques de la UPC::Ciències de la salut::Salut mental
description Background: Recent meta-analyses support the inclusion of cognitive behavioral therapy (CBT) in schizophrenia treatment. Metacognitive Training (MCT) for psychosis is a psychoeducational program derived from CBT, with most meta-analyses showing favorable results. Although meta-analyses are commonly used in clinical practice to guide evidence-based decision-making, the grading system provides complementary results by offering a structured approach for assessing the strength and reliability of evidence and deriving grades of recommendations accordingly. Methods: Our research applies the guidelines from the World Federation of Societies of Biological Psychiatry (WFSBP) to propose grades of recommendation for MCT for psychosis, analyzing 38 randomized controlled trials (RCTs) (n = 1942) and 10 meta63 analyses. The primary outcome was positive symptoms, with secondary measures including negative symptoms, general psychopathology, self-esteem, functioning, insight, and cognitive function. Results: Our findings are primarily based on the risks of bias attributed to RCTs (11 high, 19 moderate, 6 low) and, when necessary, on the overall confidence attributed to meta68 analyses (3 low, 7 critically low). According to the WFSBP guidelines, strong recommendations should be made for using MCT for psychosis to improve post-treatment positive symptoms, delusions, and total psychotic symptoms (WFSBP-grade 1). Limited recommendation (WFSBP-grade 2) could be made for using MCT to improve post72 treatment visuospatial abilities and to maintain benefits over time in psychopathology, functioning, self-esteem, episodic memory, and attention. Conclusions: MCT for psychosis is an evidence-based program, especially for positive symptoms, with long-lasting clinical benefits. These recommendations should be interpreted with caution given potential residual biases and heterogeneity among studies.
publishDate 2025
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url https://hdl.handle.net/2117/438939
https://dx.doi.org/10.1192/j.eurpsy.2025.10027
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institution Universitat Politècnica de Catalunya (UPC)
collection UPCommons. Portal del coneixement obert de la UPC
reponame_str UPCommons. Portal del coneixement obert de la UPC
instname_str Universitat Politècnica de Catalunya (UPC)
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publishDateSort 2025
author_browse Ayesa Arriola, Rosa|||0000-0003-0570-5352
Balzan, Ryan|||0000-0003-2007-4317
Berna, Fabrice
Böge, Kerem|||0000-0001-8263-4936
Cavieres, Álvaro
Fischer, Rabea
Gaweda, Lukasz
Goncalves, Adrien|||0009-0000-4834-3043
König, Caroline|||0000-0002-7543-8686
Lamarca, María
Lecomte, Tania|||0000-0002-0340-3759
Meinhart, Antonia
Moritz, Steffen
Ochoa Güerre, Susana|||0000-0001-6792-1080
Raffard, Stéphane|||0000-0001-5563-0323
score 6,9303427