The combined effect of tropicamide and phenylephrine on corneal astigmatism axis

Purpose. To analyze astigmatism axis changes after tropicamide and phenylephrine combined instillation. Method. One hundred and thirty-one eyes from sixty-six patients enrolled this cross-sectional study. An extensive ocular examination was carried out prior to tropicamide and phenylephrine instilla...

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Detalles Bibliográficos
Autores: Sánchez González, José María, Flikier, David, Nebro-Cobos, Salvador, Zamorano Martín, Francisco, Rachwani-Anil, Rahul, García Lorente, María, Borroni, Davide, Peraza-Nieves, Jorge, Rocha de Lossada, Carlos
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2022
País:España
Institución:Universidad de Sevilla (US)
Repositorio:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/160150
Acceso en línea:https://hdl.handle.net/11441/160150
https://doi.org/10.1080/02713683.2021.1971720
Access Level:acceso abierto
Palabra clave:Tropicamide
Phenylephrine
Astigmatism
Axis
Descripción
Sumario:Purpose. To analyze astigmatism axis changes after tropicamide and phenylephrine combined instillation. Method. One hundred and thirty-one eyes from sixty-six patients enrolled this cross-sectional study. An extensive ocular examination was carried out prior to tropicamide and phenylephrine instillation. Power and axis value from flat, steep, and mean keratometry were calculated using an Auto Kerato-Refractometer (AKR). Later, topography and tomography maps were evaluated with Pentacam HR® (Oculus, Wetzlar, Germany). Subsequently, a single drop of tropicamide 1% and phenylephrine hydrochloride 10% were instilled twice, with a five-minute gap between each instillation. After thirty minutes, the AKR and Pentacam HR® tests were repeated. Results. Incyclotorsion was found in 59 eyes (45.1 %) and mean absolute incyclotorsion change was 3.91 ± 3.62 degrees (0.10 to 14.20). Excyclotorsion was found in 72 eyes (54.9%) and mean excyclotorsion change was 4.99 ± 5.94 degrees (0.20 to 36.20). We observed that 74.6% and 68.1% of eyes experienced incyclotorsion and excyclotorsion within 0 to 5 degrees, respectively. Fewer patients experienced incyclotorsion and excyclotorsion changes within 5 to 10 degrees, precisely 11.8% and 19.4%, respectively. Eyes that experienced over 10 degrees of incyclotorsion and excyclotorsion were 13.6% and 12.5%, respectively. Conclusion. Astigmatism axis could change after combined tropicamide and phenylephrine instillation. Reference axis marking in astigmatism correction surgery should be performed under the same circumstances as the astigmatism axis has been measured.