Toddler Screening for Autism Spectrum Disorder: A Meta-Analysis of Diagnostic Accuracy

[EN] Great efforts focus on early detection of autism spectrum disorder, although some scientists and policy-makers have questioned early universal screening. The aim of this meta-analysis was to evaluate the diagnostic accuracy of the different screening tools. Several electronic databases were use...

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Detalhes bibliográficos
Autores: Sánchez García, Ana Belén, Galindo Villardón, Purificación, Nieto Librero, Ana Belén, Martín Rodero, Helena, Robins, Diana L.
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2019
País:España
Recursos:Universidad de Salamanca (USAL)
Repositorio:GREDOS. Repositorio Institucional de la Universidad de Salamanca
OAI Identifier:oai:gredos.usal.es:10366/154405
Acesso em linha:http://hdl.handle.net/10366/154405
Access Level:acceso abierto
Palavra-chave:M-CHAT 
Autism
Screening tools
Meta-analysis
Systematic review
HSROC
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oai_identifier_str oai:gredos.usal.es:10366/154405
network_acronym_str ES
network_name_str España
spelling Toddler Screening for Autism Spectrum Disorder: A Meta-Analysis of Diagnostic Accuracy Sánchez García, Ana Belén Galindo Villardón, Purificación Nieto Librero, Ana Belén Martín Rodero, Helena Robins, Diana L. M-CHAT  Autism Screening tools Meta-analysis Systematic review HSROC [EN] Great efforts focus on early detection of autism spectrum disorder, although some scientists and policy-makers have questioned early universal screening. The aim of this meta-analysis was to evaluate the diagnostic accuracy of the different screening tools. Several electronic databases were used to identify published studies. A Bayesian model was used to estimate the screening accuracy. The pooled sensitivity was 0.72 (95% CI 0.61-0.81), and the specificity was 0.98 (95% CI 0.97-0.99). Subgroup analyses to remove heterogeneity indicated sensitivity was 0.77 (95% CI 0.69-0.84), and specificity was 0.99 (95% CI 0.97-0.99; SD ≤ 0.01). Level 1 screening tools for ASD showed consistent statistically significant results and therefore are adequate to detect autism at 14-36 months. Fulbright Comision Lynn Kern Koegel, Universidad de Stanford, California, EE.UU. http://hdl.handle.net/10366/154405
title Toddler Screening for Autism Spectrum Disorder: A Meta-Analysis of Diagnostic Accuracy
spellingShingle Toddler Screening for Autism Spectrum Disorder: A Meta-Analysis of Diagnostic Accuracy
Sánchez García, Ana Belén
M-CHAT 
Autism
Screening tools
Meta-analysis
Systematic review
HSROC
title_short Toddler Screening for Autism Spectrum Disorder: A Meta-Analysis of Diagnostic Accuracy
title_full Toddler Screening for Autism Spectrum Disorder: A Meta-Analysis of Diagnostic Accuracy
title_fullStr Toddler Screening for Autism Spectrum Disorder: A Meta-Analysis of Diagnostic Accuracy
title_full_unstemmed Toddler Screening for Autism Spectrum Disorder: A Meta-Analysis of Diagnostic Accuracy
title_sort Toddler Screening for Autism Spectrum Disorder: A Meta-Analysis of Diagnostic Accuracy
author Sánchez García, Ana Belén
author_facet Sánchez García, Ana Belén
Galindo Villardón, Purificación
Nieto Librero, Ana Belén
Martín Rodero, Helena
Robins, Diana L.
author_role author
author2 Galindo Villardón, Purificación
Nieto Librero, Ana Belén
Martín Rodero, Helena
Robins, Diana L.
author2_role author
author
author
author
topic M-CHAT 
Autism
Screening tools
Meta-analysis
Systematic review
HSROC
topic_facet M-CHAT 
Autism
Screening tools
Meta-analysis
Systematic review
HSROC
description [EN] Great efforts focus on early detection of autism spectrum disorder, although some scientists and policy-makers have questioned early universal screening. The aim of this meta-analysis was to evaluate the diagnostic accuracy of the different screening tools. Several electronic databases were used to identify published studies. A Bayesian model was used to estimate the screening accuracy. The pooled sensitivity was 0.72 (95% CI 0.61-0.81), and the specificity was 0.98 (95% CI 0.97-0.99). Subgroup analyses to remove heterogeneity indicated sensitivity was 0.77 (95% CI 0.69-0.84), and specificity was 0.99 (95% CI 0.97-0.99; SD ≤ 0.01). Level 1 screening tools for ASD showed consistent statistically significant results and therefore are adequate to detect autism at 14-36 months.
publishDate 2019
format article
status_str publishedVersion
url http://hdl.handle.net/10366/154405
eu_rights_str_mv openAccess
publisher Lynn Kern Koegel, Universidad de Stanford, California, EE.UU.
institution Universidad de Salamanca (USAL)
collection GREDOS. Repositorio Institucional de la Universidad de Salamanca
reponame_str GREDOS. Repositorio Institucional de la Universidad de Salamanca
instname_str Universidad de Salamanca (USAL)
_version_ 1878441007089975296
publishDateSort 2019
author_browse Galindo Villardón, Purificación
Martín Rodero, Helena
Nieto Librero, Ana Belén
Robins, Diana L.
Sánchez García, Ana Belén
publisherStr Lynn Kern Koegel, Universidad de Stanford, California, EE.UU.
score 6,9303427