Supercritical CO2 assisted synthesis and concentration of monoacylglycerides rich in omega-3 polyunsaturated fatty acids
Supercritical carbon dioxide (SC−CO2) has been used as solvent in the ethanolysis of fish oil rich with omega-3 polyunsaturated fatty acids (n-3 PUFAs) by Lipozyme 435. The effect of experimental conditions: initial ethanol-to-oil molar ratio (MR, 6:1-76:1), pressure (10–30 MPa), and temperature (32...
| Autores: | , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión aceptada para publicación |
| Fecha de publicación: | 2019 |
| País: | España |
| Institución: | Universidad de Burgos (UBU) |
| Repositorio: | Repositorio Institucional de la Universidad de Burgos (RIUBU) |
| OAI Identifier: | oai:riubu.ubu.es:10259/5077 |
| Acceso en línea: | http://hdl.handle.net/10259/5077 |
| Access Level: | acceso abierto |
| Palabra clave: | Omega 3 Lipase Ethanolysis Supercritical carbon dioxide Supercritical fluid extraction Ingeniería química Chemical engineering |
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Supercritical CO2 assisted synthesis and concentration of monoacylglycerides rich in omega-3 polyunsaturated fatty acids Melgosa Gómez, Rodrigo Sanz Díez, Mª Teresa Benito Román, Oscar Illera Gigante, Alba Ester Beltrán Calvo, Sagrario Omega 3 Lipase Ethanolysis Supercritical carbon dioxide Supercritical fluid extraction Ingeniería química Chemical engineering Supercritical carbon dioxide (SC−CO2) has been used as solvent in the ethanolysis of fish oil rich with omega-3 polyunsaturated fatty acids (n-3 PUFAs) by Lipozyme 435. The effect of experimental conditions: initial ethanol-to-oil molar ratio (MR, 6:1-76:1), pressure (10–30 MPa), and temperature (323–343 K) on the reaction performance has been studied. Experimental results have been fitted to a kinetic model based on a Ping Pong Bi Bi mechanism. High accumulation of monoacylglycerides (MAGs) has been observed in short reaction times (90 min at MR = 76:1, 10 MPa, 323 K). Subsequent purification of reaction products by supercritical fluid extraction (SFE) in the experimental range 10–28 MPa and 298–333 K yielded an extract rich with fatty acid ethyl esters (FAEE) (up to 99.46%wt.), and a raffinate with up to 82.25%wt. MAG and 49.5%wt. n-3 PUFAs. Spanish Government through MINECO and the European Regional Development Fund (ERDF) for financial support [grant number CTQ2012-39131-C02-01] and RM’s and AEI’s contracts [BES-2013-063937, CTQ2015-64396-R]. To Junta de Castilla y León and ERDF for financial support [grant number BU055U16] and ÓBR’s post-doctoral contract. Elsevier http://hdl.handle.net/10259/5077 |
| title |
Supercritical CO2 assisted synthesis and concentration of monoacylglycerides rich in omega-3 polyunsaturated fatty acids |
| spellingShingle |
Supercritical CO2 assisted synthesis and concentration of monoacylglycerides rich in omega-3 polyunsaturated fatty acids Melgosa Gómez, Rodrigo Omega 3 Lipase Ethanolysis Supercritical carbon dioxide Supercritical fluid extraction Ingeniería química Chemical engineering |
| title_short |
Supercritical CO2 assisted synthesis and concentration of monoacylglycerides rich in omega-3 polyunsaturated fatty acids |
| title_full |
Supercritical CO2 assisted synthesis and concentration of monoacylglycerides rich in omega-3 polyunsaturated fatty acids |
| title_fullStr |
Supercritical CO2 assisted synthesis and concentration of monoacylglycerides rich in omega-3 polyunsaturated fatty acids |
| title_full_unstemmed |
Supercritical CO2 assisted synthesis and concentration of monoacylglycerides rich in omega-3 polyunsaturated fatty acids |
| title_sort |
Supercritical CO2 assisted synthesis and concentration of monoacylglycerides rich in omega-3 polyunsaturated fatty acids |
| author |
Melgosa Gómez, Rodrigo |
| author_facet |
Melgosa Gómez, Rodrigo Sanz Díez, Mª Teresa Benito Román, Oscar Illera Gigante, Alba Ester Beltrán Calvo, Sagrario |
| author_role |
author |
| author2 |
Sanz Díez, Mª Teresa Benito Román, Oscar Illera Gigante, Alba Ester Beltrán Calvo, Sagrario |
| author2_role |
author author author author |
| topic |
Omega 3 Lipase Ethanolysis Supercritical carbon dioxide Supercritical fluid extraction Ingeniería química Chemical engineering |
| topic_facet |
Omega 3 Lipase Ethanolysis Supercritical carbon dioxide Supercritical fluid extraction Ingeniería química Chemical engineering |
| description |
Supercritical carbon dioxide (SC−CO2) has been used as solvent in the ethanolysis of fish oil rich with omega-3 polyunsaturated fatty acids (n-3 PUFAs) by Lipozyme 435. The effect of experimental conditions: initial ethanol-to-oil molar ratio (MR, 6:1-76:1), pressure (10–30 MPa), and temperature (323–343 K) on the reaction performance has been studied. Experimental results have been fitted to a kinetic model based on a Ping Pong Bi Bi mechanism. High accumulation of monoacylglycerides (MAGs) has been observed in short reaction times (90 min at MR = 76:1, 10 MPa, 323 K). Subsequent purification of reaction products by supercritical fluid extraction (SFE) in the experimental range 10–28 MPa and 298–333 K yielded an extract rich with fatty acid ethyl esters (FAEE) (up to 99.46%wt.), and a raffinate with up to 82.25%wt. MAG and 49.5%wt. n-3 PUFAs. |
| publishDate |
2019 |
| format |
article |
| status_str |
acceptedVersion |
| url |
http://hdl.handle.net/10259/5077 |
| eu_rights_str_mv |
openAccess |
| publisher |
Elsevier |
| institution |
Universidad de Burgos (UBU) |
| collection |
Repositorio Institucional de la Universidad de Burgos (RIUBU) |
| reponame_str |
Repositorio Institucional de la Universidad de Burgos (RIUBU) |
| instname_str |
Universidad de Burgos (UBU) |
| _version_ |
1878441586382077952 |
| publishDateSort |
2019 |
| author_browse |
Beltrán Calvo, Sagrario Benito Román, Oscar Illera Gigante, Alba Ester Melgosa Gómez, Rodrigo Sanz Díez, Mª Teresa |
| publisherStr |
Elsevier |
| score |
6,924472 |